Talk:Orotic acid
 | This article is rated Start-class on Wikipedia's content assessment scale. It is of interest to the following WikiProjects: | ||||||||||
| |||||||||||
 | Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Orotic acid.
|
 | The contents of the Tricreatine orotate page were merged into Orotic acid on 11 October 2014. For the contribution history and old versions of the redirected page, please see its history. |
Untitled[edit]
not enough info. mention:
1) orotic acid is an intermediate in pyrimidine synthesis (C, T)
2) multi-organ tumour promoter
74.111.2.51 02:10, 11 December 2006 (UTC) Prof. Larry Moran, PhD. University of Toronto, Department of Biochemistry
Wrong Lemma[edit]
It's not pyrimidinecarboxylic acid, the systematic name is 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid or uracil-6-carboxylic acid, but orotic acid is more common. -- 217.224.70.151 13:09, 26 July 2006 (UTC)
Vitamin?[edit]
The article states that "...it is not a vitamin, but is instead manufactured in the body by intestinal flora." By that definition, vitamin K wouldn't be a vitamin. --ἀνυπόδητος (talk) 11:39, 31 July 2009 (UTC)
- Vitamin K is available via microbial action, but some humans still need supplements. Bearian (talk) 16:11, 2 October 2014 (UTC)
Orotic Acid Mutagen?[edit]
There is no proper citation of the rather serious claim that Orotic Acid, a necessary nutrient for humans to live, is a mutagenic compound. A google search pulled up nothing except a few abstracts about 5-Fluoro-Orotic Acid, a different compound altogether. — Preceding unsigned comment added by 65.190.21.85 (talk) 00:23, 26 December 2013 (UTC)
A Google search on 12/27/2014 turned up a materials safety data sheet for orotic acid, anhydrous (1,2,3,6-Tetrahydro-2,6-dioxo-4- pyrimidinecarboxylic Acid; 6-Uracilcarboxylic Acid) from ScienceLab.com that states: "Chronic Effects on Humans: MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/ or yeast." [1] Also found this substance listed as having an RTECS class of Mutagen. [2]
References
Tricreatine orotate[edit]
This article has been proposed for deletion. However, otherwise non-notable salts of an acid should be merged into the parent article when feasible. Bearian (talk) 16:12, 2 October 2014 (UTC)
Done. The tricreatine orotate article was at best poorly sourced, but I claim no expertise in this area. Hopefully someone with a greater knowledge of chemistry can provide a decent source for the merged content. Euryalus (talk) 12:45, 11 October 2014 (UTC)
Pronunciation[edit]
Because of the unfortunate name of B¹³, I propose the correct pronunciation be added to the article to prevent confusion. 68.185.117.66 (talk) 15:04, 6 November 2022 (UTC)